Emerges with $8.3M to Advance AI-Driven Precision Medicine for Autoimmune Diseases

SUMMARY

• Promise Bio - A precision medicine startup with a focus on immune-mediated diseases, raises $8.3M seed round led by Awz Ventures with AION Lab also participating, backed by AstraZeneca & Pfizer.
• Technology: Proprietary PROMISE platform combines epiproteomics and AI to predict treatment responses, analyze PTMs and assist in drug development.
• Partnerships with AstraZeneca and Pfizer bring world-class expertise accelerating the integration into drug development pipelines.

Promise Bio Emerges with $8.3M to Advance AI-Driven Precision Medicine for Autoimmune Diseases

Promise Bio is an innovative startup that aims to revolutionize the treatment of immune-mediated diseases. It has announced its emergence from stealth mode with an $8.3 million seed investment. The funding will help accelerate the development of Promise Bio's cutting-edge computational platform, which integrates epiproteomics and artificial intelligence to predict patient treatment responses and support drug development in immune-mediated diseases.

"Current biological treatments for autoimmune diseases fail for many patients, with only 30-40% of patients achieving significant remission," said Ronel Veksler, Co-founder and CEO of Promise Bio. "At Promise Bio, our goal is to eliminate the trial-and-error approach and introduce data-driven decision-making tools. The key lies in focusing on the right biological data—proteins, which are the building blocks of life. Our PROMISE platform does exactly that, bringing us closer to the era of precision medicine for diseases that currently lack effective treatments."

Promise Bio's platform is founded on groundbreaking research into protein modifications, led by Co-founder & CTO Dr. Assaf Kacen at the Weizmann Institute of Science. Published in Nature Biotechnology in 2023, this research underlies the company's technology. The platform enables the large-scale profiling of PTMs using mass-spectrometry data without the need for custom lab procedures, which enables more accurate insights into immune response mechanisms.

"Our platform enables us not only to measure the quantities of proteins but the alterations they undergo due to disease. With AI-powered analysis, we can interpret these modifications almost like a high-resolution view of the underlying biology, providing a clearer understanding of disease mechanisms," Dr. Kacen said.

The seed investment totaling $8.3 million has been led by Awz Ventures, with additional funding being provided by AION Lab's venture seeding track backed by AstraZeneca and Pfizer. This financial support will aid the rapid scaling of the platform at Promise Bio so the company can expand research capabilities and further develop technology. The strategic partnerships with AstraZeneca and Pfizer bring more than funding to the table; they bring industry expertise and global networks that allow Promise Bio to integrate its platform into drug development pipelines.

"Precise integration of epiproteomics and AI holds great promise to revolutionize treatment approaches in immune-mediated diseases," said Mati Gill, CEO of AION Labs. "We are proud to support this groundbreaking company and contribute to advancements in precision medicine."

Promise Bio is a precision medicine company transforming the treatment of immune-mediated diseases. Founded on ground-breaking science developed by the Weizmann Institute of Science, the company works through its proprietary epiproteomics platform to research proteins and their PTMs. The platform is now capable of large-scale profiling, thus providing researchers with greater insights into disease mechanisms and tailoring therapies for disease and finding new drug targets.

"Awz is thrilled to support Promise Bio's vision," said Yaron Ashkenazi, Founder & Managing Partner of Awz. "We believe in the company's unique approach and leadership, and we're confident that Promise Bio will set new standards in personalized medicine and improve patient outcomes."

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